The flight will cover a whopping 9000 nautical miles (16,700km) and take almost 19 hours. The airline will operate the flight three times a week.
World's longest range airliner makes its first test flight
Watch the first test flight of the Airbus A350-900ULR (Ultra Long Range) plane. The new aircraft will take off for Singapore Airlines on the world's longest route (Singapore to New York) in October 2018.
Singapore Airlines will fly the new Airbus A350-900ULR (for "Ultra Long Range") on the route. The airline is the launch customer for the new aircraft and will take delivery of its first A350-900ULR in September.
Signapore currently has 21 A350s in its fleet with 46 more on order, including seven of the ULR long-range version.
In a bold move, the plane flying the Singapore to New York route will only offer premium seating, with 67 business class and 94 premium economy class seats. This is a similar set-up to when Singapore previously flew this same route, using a four-engine Airbus A340 which featured only business class seats.
The fuel inefficiency of the A340 saw the route become unprofitable and it was dropped in 2013 after less than 10 years in service.
Since then, new fuel-efficient aircraft such as the A350 and the Boeing 787 Dreamliner have seen an increase in the number of ultra-long-haul routes airlines are flying.
Earlier this year, Qantas started the first non-stop flights between Australia and the UK, launching its Perth to London route with a 787-9 Dreamliner. New Zealand, meanwhile, plays host to the longest flight route in the world, Doha to Auckland flown by Qatar Airways (14,529km), along with the third longest - Dubai to Auckland (14,200km).